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ALL Methylation Supplementary Table 8

Overlap of normal T- v B-cell and leukemic T- v B-cell methylation signatures.

ComparisonSignature 1 Probe NumberSignature 2 Probe NumberOverlap Probe NumberSignature 1 Residual Probe NumberSignature 2 Residual Probe NumberSignature 1 Residual/Probe NumberOverlap Ratio
Subtract Hyper signatures [Normal T v B] (FDR=0.1, Delta1) from [T- v B-ALL] (FDR=0.1, Delta1) 897 2463 413 484 2050 54.00% 39.70%
Subtract Hypo signatures [Normal T v B] (FDR=0.1, Delta1) from [T- v B-ALL] (FDR=0.1, Delta1) 422 1403 110 312 1293 73.90%  
Subtract Hyper signatures [Normal T v B] (FDR=1, Delta1) from [T- v B-ALL] (FDR=1, Delta1) 897 2545 413 484 2132 54.00% 39.70%
Subtract Hyper signatures [Normal T v B] (FDR=1, Delta1) from [T- v B-ALL] (FDR=1, Delta1) 422 1403 110 312 1293 73.90%  
Subtract Hyper signatures [Normal T v B] (FDR=1, Delta0.5) from [T- v B-ALL] (FDR=1, Delta0.5) 2214 5728 1086 1128 4642 50.90% 38.90%
Subtract Hyper signatures [Normal T v B] (FDR=1, Delta0.5) from [T- v B-ALL] (FDR=1, Delta0.5) 1923 6354 522 1401 5832 72.90%  
Subtract Hyper signatures [Normal T v B] (FDR=1, Delta2) from [T- v B-ALL] (FDR=1, Delta2) 181 345 59 122 286 67.40% 31.30%
Subtract Hyper signatures [Normal T v B] (FDR=1, Delta2) from [T- v B-ALL] (FDR=1, Delta2) 46 175 12 34 163 73.90%