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ALL Methylation Supplementary Table 4-7

List of highly correlated Refseq genes with downregulated FDR<0.05 and hypermethylated FDR<0.05 in MLLr_B

RefSeq Genes Annotation Cytoband Max Pearson Corr Estimate P Max Pearson Corr Max Pearson Corr Affy Probe GEP FC GEP FDR GEP Common Rank Max Pearson Corr HELP Probe MET Delta MET FDR
NM_007161 LST1 leukocyte specific transcript 1 chr6p21.3 0.693576754 0 214181_x_at 4.887604763 4.70E-06 129 / 12428 MSPI0406S00315957 1.791904942 2.45E-07
NM_002341 LTB lymphotoxin beta (TNF superfamily, member 3) chr6p21.3 0.62798234 2.66E-15 207339_s_at 2.982477847 0.005969006 714 / 12428 MSPI0406S00315958 1.05465917 0.006080861
NM_001017520 DNTT deoxynucleotidyltransferase, terminal chr10q23-q24 0.582187267 7.02E-13 210487_at 7.517465097 2.60E-11 21 / 12428 MSPI0406S00529880 1.214051187 6.20E-06
NM_014957 DENND3 DENN/MADD domain containing 3 chr8q24.3 0.574958436 1.56E-12 212975_at 2.159564849 0.003137742 595 / 12428 MSPI0406S00447241 1.029212395 2.12E-07
NM_002201 ISG20 interferon stimulated exonuclease gene 20kDa chr15q26 0.564505537 4.77E-12 33304_at 1.6242076 0.02980097 1316 / 12428 MSPI0406S00726380 0.854298767 0.013438412
NM_022081 HPS4 Hermansky-Pudlak syndrome 4 chr22cen-q12.3 0.561777186 6.35E-12 218402_s_at 2.491242314 2.73E-05 185 / 12428 MSPI0406S00962017 1.003799513 0.004837738
NM_024943 TMEM156 transmembrane protein 156 chr4p14 0.555138815 1.26E-11 220169_at 1.7400458 0.040877241 1455 / 12428 MSPI0406S00228312 0.473076329 0.034045882
NM_014674 EDEM1 ER degradation enhancer, mannosidase alpha-like 1 chr3p26.1 0.550967283 1.92E-11 203279_at 2.079671027 1.08E-05 151 / 12428 MSPI0406S00163318 1.429280571 1.19E-18
NM_001470 GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 chr6p21.31 0.537646333 7.14E-11 203146_s_at 2.001279149 0.001116906 436 / 12428 MSPI0406S00314790 0.834798382 0.047853127
NM_002039 GAB1 GRB2-associated binding protein 1 chr4q31.21 0.523017676 2.82E-10 207112_s_at 2.18210736 0.001034066 427 / 12428 MSPI0406S00245299 2.834707225 1.12E-09
NM_002217 ITIH3 inter-alpha (globulin) inhibitor H3 chr3p21.2-p21.1 0.520271811 3.63E-10 205755_at 2.111122365 0.002733878 565 / 12428 MSPI0406S00180110 2.204749169 3.55E-13
NM_001803 CD52 CD52 molecule chr1p36 0.497793561 2.61E-09 204661_at 2.925692175 3.67E-05 200 / 12428 MSPI0406S00022814 1.705099459 1.23E-17
NM_145290 GPR125 G protein-coupled receptor 125 chr4p15.2 0.488283699 5.77E-09 210473_s_at 1.817910501 0.041166636 1462 / 12428 MSPI0406S00225214 0.54237142 0.04356546
NM_006255 PRKCH protein kinase C, eta chr14q22-q23 0.486486656 6.68E-09 218764_at 3.964911559 6.88E-15 9 / 12428 MSPI0406S00677327 3.603738077 3.75E-15
NM_005567 LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein chr17q25 0.446470156 1.43E-07 200923_at 2.128432722 0.003576658 619 / 12428 MSPI0406S00829919 0.511677218 0.004368972
NM_002101 GYPC glycophorin C (Gerbich blood group) chr2q14-q21 0.439256083 2.39E-07 202947_s_at 1.822254364 0.005449027 700 / 12428 MSPI0406S00129703 1.371751069 1.20E-05
NM_007079 PTP4A3 protein tyrosine phosphatase type IVA, member 3 chr8q24.3 0.437582839 2.68E-07 206574_s_at 3.283299377 0.0030819 589 / 12428 MSPI0406S00447631 0.895898774 1.85E-07
NM_002117 HLA-C major histocompatibility complex, class I, C chr6p21.3 0.429663647 4.63E-07 214459_x_at 1.719191024 2.40E-05 179 / 12428 MSPI0406S00315789 1.954337877 7.64E-17
NM_005230 ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) chr12q23 0.425426664 6.17E-07 221773_at 8.696492896 2.88E-12 16 / 12428 MSPI0406S00623057 0.547291057 6.07E-06
NM_012068 ATF5 activating transcription factor 5 chr19q13.3 0.423483089 7.02E-07 204998_s_at 1.392360796 0.047593015 1551 / 12428 MSPI0406S00902297 0.902134085 0.002716831
NM_024330 SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 chr1q21.3 0.413863967 1.32E-06 222217_s_at 1.712930532 0.034126617 1372 / 12428 MSPI0406S00056272 0.831906939 1.73E-09
NM_003818 CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 chr20p13 0.40938927 1.76E-06 212862_at 1.603610525 6.74E-05 236 / 12428 MSPI0406S00912738 1.553016025 3.45E-05
NM_016215 EGFL7 EGF-like-domain, multiple 7 chr9q34.3 0.403272524 2.59E-06 218825_at 2.720564774 0.003491401 615 / 12428 MSPI0406S00494995 0.987950413 1.39E-09
NM_213602 SIGLEC15 sialic acid binding Ig-like lectin 15 chr18q12.3 0.390809721 5.55E-06 215856_at 1.783029313 0.04439595 1505 / 12428 MSPI0406S00847655 1.005348062 0.000295752
NM_015015 KDM4B lysine (K)-specific demethylase 4B chr19p13.3 0.365263517 2.42E-05 212495_at 1.664021408 0.00021272 292 / 12428 MSPI0406S00865599 1.208432591 0.001521665
NM_001145426 CSDA cold shock domain protein A chr12p13.1 0.360067411 3.21E-05 201161_s_at 2.053036128 0.002894427 575 / 12428 MSPI0406S00602696 1.089871075 0.014903383
NM_018990 SASH3 SAM and SH3 domain containing 3 chrXq26 0.358447322 3.50E-05 204923_at 1.465876719 0.009429516 825 / 12428 MSPI0406S01013205 0.335366081 0.011500946
NM_003262 SEC62 SEC62 homolog (S. cerevisiae) chr3q26.2 0.354938 4.23E-05 208942_s_at 1.376458246 0.001036664 428 / 12428 MSPI0406S00204488 2.186009243 6.95E-12
NM_003944 SELENBP1 selenium binding protein 1 chr1q21-q22 0.344756731 7.21E-05 214433_s_at 1.951413535 0.04544001 1518 / 12428 MSPI0406S00055314 0.587926232 0.002192311
NM_005514 HLA-B major histocompatibility complex, class I, B chr6p21.3 0.333986677 0.000124335 208729_x_at 1.878075004 7.22E-06 143 / 12428 MSPI0406S00315811 1.776132246 5.26E-19
NM_014666 CLINT1 clathrin interactor 1 chr5q33.3 0.33392991 0.000124686 201768_s_at 1.330585151 0.007659825 771 / 12428 MSPI0406S00292577 1.54220687 1.36E-08
NM_004815 ARHGAP29 Rho GTPase activating protein 29 chr1p22.1-p21.3 0.333216075 0.000129178 203910_at 2.275721813 0.012965434 932 / 12428 MSPI0406S00046748 0.483988462 0.00246204
NM_014708 KNTC1 kinetochore associated 1 chr12q24.31 0.330985235 0.000144207 206316_s_at 1.461351868 0.047639548 1552 / 12428 MSPI0406S00635408 0.62706669 0.014534929
NM_006235 POU2AF1 POU class 2 associating factor 1 chr11q23.1 0.292333704 0.000852924 205267_at 1.769572299 0.017458404 1047 / 12428 MSPI0406S00585713 1.285394571 0.000918434
NM_001013694 SRRD SRR1 domain containing chr22q12.1 0.286186336 0.001107191 213608_s_at 1.600704239 0.002792744 569 / 12428 MSPI0406S00962017 1.003799513 0.004837738
NM_005730 CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 chr12q13-q15 0.282941293 0.001267729 203445_s_at 1.242427132 0.023205253 1185 / 12428 MSPI0406S00616618 1.326049756 1.22E-06
NM_153045 C9orf91 chromosome 9 open reading frame 91 chr9q32 0.281742247 0.00133223 221865_at 1.363460052 0.000761167 385 / 12428 MSPI0406S00479393 0.766138946 0.009653524
NR_002323 TUG1 taurine upregulated 1 (non-protein coding) chr22q12.2 0.2801283 0.001423773 212337_at 1.247333902 0.046410845 1534 / 12428 MSPI0406S00964918 0.129612095 0.011778824
NM_000858 GUK1 guanylate kinase 1 chr1q32-q41 0.274842254 0.001765147 200075_s_at 1.823547963 5.43E-07 87 / 12428 MSPI0406S00078498 2.255061825 5.65E-12
NM_003025 SH3GL1 SH3-domain GRB2-like 1 chr19p13.3 0.265609933 0.002543805 201851_at 1.713193047 0.011565491 888 / 12428 MSPI0406S00864775 0.296056422 0.043985859
NM_020179 C11orf75 chromosome 11 open reading frame 75 chr11q13.3-q23.3 0.244288239 0.005643034 219806_s_at 2.445610518 5.23E-06 134 / 12428 MSPI0406S00582722 0.734905605 0.029377368
NM_007021 C10orf10 chromosome 10 open reading frame 10 chr10q11.21 0.243713812 0.005760333 209182_s_at 2.203812374 0.002980256 582 / 12428 MSPI0406S00514015 0.412701396 0.040255795
NM_023015 INTS3 integrator complex subunit 3 chr1q21.3 0.24314599 0.005878414 202809_s_at 1.531520336 0.034155451 1373 / 12428 MSPI0406S00056245 0.599354532 4.17E-07
NM_001005158 SFMBT1 Scm-like with four mbt domains 1 chr3p21.1 0.238495689 0.006929452 213370_s_at 1.358155097 0.009370976 823 / 12428 MSPI0406S00180268 0.645628431 0.025325576
NM_006504 PTPRE protein tyrosine phosphatase, receptor type, E chr10q26 0.237203252 0.007249738 221840_at 1.569465374 0.018640495 1080 / 12428 MSPI0406S00543310 2.420032039 8.33E-13
NM_004457 ACSL3 Acyl-CoA synthetase long-chain family member 3 chr2q34-q35 0.233692131 0.008187065 201662_s_at 1.417634915 0.010894865 871 / 12428 MSPI0406S00151270 0.772907362 0.017299189
NM_001009932 DNASE1L1 deoxyribonuclease I-like 1 chrXq28 0.228883286 0.009644106 203912_s_at 2.024050309 3.54E-05 198 / 12428 MSPI0406S01020170 0.530894691 0.035240266
NM_004050 BCL2L2 BCL2-like 2 chr14q11.2-q12 0.218944673 0.013395856 209311_at 1.416106056 0.00036509 333 / 12428 MSPI0406S00668977 1.14745935 2.01E-05
NM_006932 SMTN smoothelin chr22q12.2 0.204834071 0.020883182 207390_s_at 1.679555059 0.048420583 1566 / 12428 MSPI0406S00964987 1.457348008 2.11E-06
NM_015562 UBXN7 UBX domain protein 7 chr3q29 0.192715722 0.029952837 217100_s_at 1.523795924 0.000541154 364 / 12428 MSPI0406S00213355 0.762897748 0.002590586
NM_015069 ZNF423 zinc finger protein 423 chr16q12 0.179387167 0.043590943 214761_at 2.423594451 1.83E-05 166 / 12428 MSPI0406S00758458 0.976702424 0.03721138
NM_005197 FOXN3 forkhead box N3 chr14q31.3 0.175907334 0.047902946 205022_s_at 1.605217849 0.000313521 322 / 12428 MSPI0406S00686431 1.732776138 4.74E-09