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ALL Methylation Supplementary Table 4-1

List of highly correlated Refseq genes with downregulated FDR<0.05 and hypermethylated FDR<0.05 in T-ALL

RefSeq Genes Annotation Cytoband Max Pearson Corr Estimate P Max Pearson Corr Max Pearson Corr Affy Probe GEP FC GEP FDR GEP Common Rank Max Pearson Corr HELP Probe MET Delta MET FDR
NM_013378 VPREB3 pre-B lymphocyte 3 chr22q11.23|22q11 0.784744031 0 220068_at 21.58091091 3.08E-31 16 / 12428 MSPI0406S00960076 3.72194939 2.98E-87
NM_001114094 BLNK B-cell linker chr10q23.2-q23.33 0.741619233 0 207655_s_at 14.40439696 5.27E-35 5 / 12428 MSPI0406S00529872 3.648877061 6.12E-55
NM_003877 SOCS2 suppressor of cytokine signaling 2 chr12q 0.722262065 0 203373_at 8.924202252 3.23E-17 113 / 12428 MSPI0406S00622030 0.898731451 1.68E-08
NM_000626 CD79B CD79b molecule, immunoglobulin-associated beta chr17q23 0.696507731 0 205297_s_at 7.499343274 3.17E-32 13 / 12428 MSPI0406S00819368 3.315305812 1.13E-24
NM_001017520 DNTT deoxynucleotidyltransferase, terminal chr10q23-q24 0.696389401 0 210487_at 3.371135806 4.00E-05 924 / 12428 MSPI0406S00529880 0.734732878 0.00385653
NM_001025158 CD74 CD74 molecule, major histocompatibility complex, class II invariant chain chr5q32 0.695086285 0 209619_at 10.50124539 7.15E-38 3 / 12428 MSPI0406S00290338 1.888909544 1.21E-33
NM_024330 SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 chr1q21.3 0.684481612 0 222217_s_at 4.402158175 3.23E-17 112 / 12428 MSPI0406S00056272 2.689051171 5.29E-46
NM_002123 HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 chr6p21.3 0.68052751 0 209480_at 3.898817535 5.72E-06 748 / 12428 MSPI0406S00316874 0.536347212 0.022230953
NM_001783 CD79A CD79a molecule, immunoglobulin-associated alpha chr19q13.2 0.654445666 0 205049_s_at 5.59779464 3.10E-29 24 / 12428 MSPI0406S00894273 1.751754074 1.10E-28
NM_002039 GAB1 GRB2-associated binding protein 1 chr4q31.21 0.648497584 0 207112_s_at 4.661966847 1.18E-16 123 / 12428 MSPI0406S00245299 2.520172194 1.99E-10
NM_002201 ISG20 interferon stimulated exonuclease gene 20kDa chr15q26 0.613283951 0 33304_at 2.54717525 4.37E-10 345 / 12428 MSPI0406S00726380 1.456329126 2.34E-09
NM_001142370 PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) chr2q21.1 0.612368077 0 213521_at 2.088021416 1.82E-10 324 / 12428 MSPI0406S00131861 2.566920974 2.73E-24
NM_003263 TLR1 toll-like receptor 1 chr4p14 0.610836388 0 210176_at 1.815906944 2.38E-07 565 / 12428 MSPI0406S00228209 2.677105489 3.26E-19
NM_002217 ITIH3 inter-alpha (globulin) inhibitor H3 chr3p21.2-p21.1 0.59477056 4.44E-16 205755_at 2.30119708 1.94E-06 669 / 12428 MSPI0406S00180110 2.653303247 1.10E-20
NM_001803 CD52 CD52 molecule chr1p36 0.593929444 4.44E-16 34210_at 2.949810675 1.67E-08 449 / 12428 MSPI0406S00022814 2.065061693 7.53E-23
NM_001142286 SMC6 structural maintenance of chromosomes 6 chr2p24.2 0.579537436 3.33E-15 218781_at 1.872165845 1.67E-08 450 / 12428 MSPI0406S00095781 1.766062963 1.31E-18
NM_019086 FLJ20674 hypothetical protein FLJ20674 chr12q24.23 0.578116797 4.22E-15 220137_at 2.012106134 1.30E-12 223 / 12428 MSPI0406S00632198 3.289319642 3.98E-72
NM_022081 HPS4 Hermansky-Pudlak syndrome 4 chr22cen-q12.3 0.57113896 1.04E-14 218402_s_at 1.962425338 4.81E-05 943 / 12428 MSPI0406S00962017 0.921590848 0.001085247
NM_003730 RNASET2 ribonuclease T2 chr6q27 0.550593069 1.39E-13 217984_at 2.266749069 1.12E-08 434 / 12428 MSPI0406S00349065 1.485415804 3.01E-25
NM_001470 GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 chr6p21.31 0.540349127 4.73E-13 203146_s_at 1.667080973 0.001177748 1412 / 12428 MSPI0406S00314790 2.720633096 2.95E-19
NM_001135585 SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 chr1p36.2 0.532818145 1.14E-12 204430_s_at 5.337941456 1.66E-11 262 / 12428 MSPI0406S00008592 0.580425563 0.007133431
NM_001769 CD9 CD9 molecule chr12p13.3 0.532074144 1.24E-12 201005_at 13.66445993 2.06E-14 165 / 12428 MSPI0406S00600155 1.399029714 5.77E-14
NM_015150 RFTN1 raftlin, lipid raft linker 1 chr3p25.1-p24.3 0.530890918 1.42E-12 212646_at 2.230987585 1.86E-11 263 / 12428 MSPI0406S00168555 1.213164129 2.71E-05
NM_001164281 TRAF3IP2 TRAF3 interacting protein 2 chr6q21 0.520550642 4.52E-12 215411_s_at 3.591145986 6.06E-16 131 / 12428 MSPI0406S00334940 1.664419592 1.61E-33
NM_007128 VPREB1 pre-B lymphocyte 1 chr22q11.2|22q11.22 0.515935354 7.49E-12 221349_at 12.64347429 3.83E-21 79 / 12428 MSPI0406S00959025 0.277750747 0.014992945
NM_033554 HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 chr6p21.3 0.513910841 9.33E-12 211991_s_at 14.99204043 6.00E-30 20 / 12428 MSPI0406S00317006 1.136498301 2.27E-08
NM_014674 EDEM1 ER degradation enhancer, mannosidase alpha-like 1 chr3p26.1 0.513697371 9.55E-12 203279_at 1.79169918 4.47E-06 725 / 12428 MSPI0406S00163315 2.602567677 2.39E-44
NM_002121 HLA-DPB1 major histocompatibility complex, class II, DP beta 1 chr6p21.3 0.504542551 2.53E-11 201137_s_at 9.318840032 3.17E-28 27 / 12428 MSPI0406S00317006 1.136498301 2.27E-08
NM_006504 PTPRE protein tyrosine phosphatase, receptor type, E chr10q26 0.503544419 2.81E-11 221840_at 3.666063486 1.35E-19 86 / 12428 MSPI0406S00543311 1.829923956 1.21E-21
NM_004711 SYNGR1 synaptogyrin 1 chr22q13.1 0.499778505 4.15E-11 213854_at 2.496392755 3.82E-11 271 / 12428 MSPI0406S00971311 2.003718168 5.63E-13
NM_001771 CD22 CD22 molecule chr19q13.1 0.494653514 7.01E-11 38521_at 4.529786089 1.69E-26 34 / 12428 MSPI0406S00888496 2.340081911 3.46E-15
NM_004414 RCAN1 regulator of calcineurin 1 chr21q22.1-q22.2|21q22.12 0.494471313 7.14E-11 208370_s_at 3.44767046 4.91E-10 347 / 12428 MSPI0406S00945298 0.932576112 2.72E-07
NM_005026 PIK3CD phosphoinositide-3-kinase, catalytic, delta polypeptide chr1p36.2 0.493404014 7.95E-11 203879_at 2.216301787 2.07E-13 190 / 12428 MSPI0406S00009266 1.227183354 4.63E-16
NM_002117 HLA-C major histocompatibility complex, class I, C chr6p21.3 0.491009602 1.01E-10 214459_x_at 1.827492281 2.50E-07 568 / 12428 MSPI0406S00315789 1.178747598 5.72E-07
NM_006235 POU2AF1 POU class 2 associating factor 1 chr11q23.1 0.488411537 1.31E-10 205267_at 6.293545876 2.04E-23 63 / 12428 MSPI0406S00585713 1.684062159 3.72E-09
NM_021182 HMHB1 histocompatibility (minor) HB-1 chr5q31.3 0.487558037 1.43E-10 208302_at 1.938261169 5.90E-10 353 / 12428 MSPI0406S00288561 2.905400037 2.84E-77
NM_001006109 C3orf37 Chromosome 3 open reading frame 37 chr3q21.3 0.484495436 1.93E-10 201678_s_at 1.579840986 8.81E-07 629 / 12428 MSPI0406S00196352 1.584511042 2.49E-36
NM_005230 ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) chr12q23 0.484039038 2.02E-10 206127_at 2.471533733 4.24E-08 488 / 12428 MSPI0406S00623057 1.026020384 4.40E-16
NM_016215 EGFL7 EGF-like-domain, multiple 7 chr9q34.3 0.477634679 3.76E-10 218825_at 2.713595236 2.65E-05 872 / 12428 MSPI0406S00494995 1.382168326 1.23E-19
NM_014430 CIDEB cell death-inducing DFFA-like effector b chr14q12 0.468928578 8.58E-10 221188_s_at 1.484611774 0.001938375 1517 / 12428 MSPI0406S00669634 3.018915574 1.31E-38
NM_001560 IL13RA1 interleukin 13 receptor, alpha 1 chrXq24 0.46598853 1.13E-09 201887_at 1.752615547 0.000774975 1332 / 12428 MSPI0406S01010806 0.77358999 0.005574155
NM_000476 AK1 adenylate kinase 1 chr9q34.1 0.465524819 1.18E-09 202587_s_at 2.436292247 2.84E-12 236 / 12428 MSPI0406S00484960 1.301273998 5.99E-09
NM_006747 SIPA1 signal-induced proliferation-associated 1 chr11q13 0.458798887 2.18E-09 204164_at 2.312700512 1.58E-11 261 / 12428 MSPI0406S00570952 0.993453368 1.14E-09
NM_007079 PTP4A3 protein tyrosine phosphatase type IVA, member 3 chr8q24.3 0.456493438 2.68E-09 209695_at 1.577397571 0.000528141 1258 / 12428 MSPI0406S00447631 0.677378852 1.83E-06
NM_004425 ECM1 extracellular matrix protein 1 chr1q21 0.455866176 2.83E-09 209365_s_at 3.101432141 6.44E-07 618 / 12428 MSPI0406S00054603 1.345973208 2.49E-10
NM_001782 CD72 CD72 molecule chr9p13.3 0.453365179 3.54E-09 215925_s_at 7.168070111 7.18E-21 80 / 12428 MSPI0406S00459439 0.779567144 3.40E-11
NM_005582 CD180 CD180 molecule chr5q12 0.45124868 4.27E-09 206206_at 1.904759813 0.000204397 1101 / 12428 MSPI0406S00271573 0.577437862 0.030382834
NM_004119 FLT3 fms-related tyrosine kinase 3 chr13q12 0.451111966 4.32E-09 206674_at 3.675921243 5.55E-08 499 / 12428 MSPI0406S00647380 0.546198162 0.006164801
NM_031409 CCR6 chemokine (C-C motif) receptor 6 chr6q27 0.450420232 4.59E-09 206983_at 1.557111185 0.006013574 1876 / 12428 MSPI0406S00349145 2.961493542 1.26E-16
NM_001160 APAF1 apoptotic peptidase activating factor 1 chr12q23 0.442088665 9.47E-09 204859_s_at 1.261033893 0.026513077 2547 / 12428 MSPI0406S00623620 1.009079157 4.49E-05
NM_002122 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 chr6p21.3 0.440401304 1.09E-08 212671_s_at 8.780543724 1.12E-16 122 / 12428 MSPI0406S00316861 0.813526076 0.011660571
NM_002397 MEF2C myocyte enhancer factor 2C chr5q14 0.438577854 1.28E-08 209200_at 17.46850548 3.80E-26 40 / 12428 MSPI0406S00276770 1.027288188 0.000964669
NM_001025160 CD97 CD97 molecule chr19p13 0.437354566 1.42E-08 202910_s_at 1.480060623 0.030567257 2626 / 12428 MSPI0406S00875960 1.00521792 1.63E-15
NM_004479 FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) chr9q34.3 0.433440129 1.97E-08 210506_at 1.580262278 0.044210313 2875 / 12428 MSPI0406S00495547 0.729978847 9.98E-07
NM_005775 SORBS3 sorbin and SH3 domain containing 3 chr8p21.3 0.430261994 2.56E-08 209253_at 2.401618486 2.70E-12 234 / 12428 MSPI0406S00418578 0.781098976 2.45E-06
NM_005514 HLA-B major histocompatibility complex, class I, B chr6p21.3 0.426778008 3.40E-08 208729_x_at 2.295880989 1.38E-09 375 / 12428 MSPI0406S00315809 0.372968125 0.008585087
NM_001142523 IRAK3 interleukin-1 receptor-associated kinase 3 chr12q14.3 0.42486291 3.98E-08 213817_at 3.473094719 2.72E-08 466 / 12428 MSPI0406S00618117 1.180283661 1.74E-06
NM_004157 PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha chr3p21.3-p21.2 0.422596724 4.77E-08 213052_at 1.254447692 1.26E-05 815 / 12428 MSPI0406S00177107 1.616787157 1.21E-23
NM_012408 ZMYND8 zinc finger, MYND-type containing 8 chr20q13.12 0.422113943 4.96E-08 209048_s_at 1.668514806 3.60E-10 341 / 12428 MSPI0406S00927996 2.755167751 8.65E-24
NM_004050 BCL2L2 BCL2-like 2 chr14q11.2-q12 0.419067344 6.33E-08 209311_at 1.410115048 7.06E-06 766 / 12428 MSPI0406S00668977 1.738418388 1.08E-14
NM_001068 TOP2B topoisomerase (DNA) II beta 180kDa chr3p24 0.417002381 7.46E-08 211987_at 1.950943375 3.06E-14 170 / 12428 MSPI0406S00169952 2.387906031 1.11E-32
NM_001715 BLK B lymphoid tyrosine kinase chr8p23-p22 0.414471248 9.10E-08 206255_at 2.109188532 0.002629849 1588 / 12428 MSPI0406S00414852 0.788876235 1.56E-11
NM_000061 BTK Bruton agammaglobulinemia tyrosine kinase chrXq21.33-q22 0.41107636 1.19E-07 205504_at 4.475938738 1.03E-29 21 / 12428 MSPI0406S01007568 1.255027494 6.17E-06
NM_006271 S100A1 S100 calcium binding protein A1 chr1q21 0.408607289 1.43E-07 205334_at 2.118657985 6.02E-06 755 / 12428 MSPI0406S00056135 2.014189314 8.16E-13
NM_014146 LAT2 linker for activation of T cells family, member 2 chr7q11.23 0.407130693 1.61E-07 221581_s_at 5.738092836 8.34E-18 99 / 12428 MSPI0406S00379603 1.18950007 1.29E-14
NM_213602 SIGLEC15 sialic acid binding Ig-like lectin 15 chr18q12.3 0.405870554 1.77E-07 215856_at 1.568115495 0.021448509 2412 / 12428 MSPI0406S00847655 1.807107215 1.95E-15
NM_001024372 BAALC brain and acute leukemia, cytoplasmic chr8q22.3 0.402751627 2.24E-07 218899_s_at 1.706585148 0.036387674 2735 / 12428 MSPI0406S00438806 1.192316543 4.02E-06
NM_001024211 S100A13 S100 calcium binding protein A13 chr1q21 0.400761323 2.60E-07 202598_at 2.15828154 4.17E-12 243 / 12428 MSPI0406S00056131 1.1608425 0.001301415
NM_013258 PYCARD PYD and CARD domain containing chr16p12-p11.2 0.400625459 2.63E-07 221666_s_at 1.433343262 0.015372365 2252 / 12428 MSPI0406S00755614 0.949068844 2.00E-12
NM_007271 STK38 serine/threonine kinase 38 chr6p21 0.39844181 3.09E-07 202951_at 1.923749384 9.88E-09 430 / 12428 MSPI0406S00319698 1.787814448 5.58E-15
NM_005605 PPP3CC protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform chr8p21.3 0.393950237 4.31E-07 207000_s_at 3.881409031 1.37E-23 59 / 12428 MSPI0406S00418534 1.358714996 5.12E-11
NM_015147 CEP68 centrosomal protein 68kDa chr2p14 0.393946044 4.31E-07 207971_s_at 1.523008786 6.25E-05 980 / 12428 MSPI0406S00110875 1.017346752 1.20E-17
NM_001945 HBEGF heparin-binding EGF-like growth factor chr5q23 0.392576338 4.76E-07 203821_at 3.020696025 0.0001073 1031 / 12428 MSPI0406S00286985 3.283937139 3.66E-19
NM_001143919 LTB4R leukotriene B4 receptor chr14q11.2-q12 0.392251603 4.87E-07 210128_s_at 1.874522552 3.08E-07 580 / 12428 MSPI0406S00669634 3.018915574 1.31E-38
NM_002649 PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide chr7q22.3 0.390064865 5.71E-07 206369_s_at 2.865061406 1.52E-10 317 / 12428 MSPI0406S00391334 1.391994553 1.64E-07
NM_003262 SEC62 SEC62 homolog (S. cerevisiae) chr3q26.2 0.389674624 5.88E-07 208942_s_at 1.174956457 0.034989511 2720 / 12428 MSPI0406S00204488 2.35428282 1.16E-16
NM_001135191 ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 chr2p25|2p24 0.38837741 6.45E-07 206414_s_at 1.703379367 0.003741589 1697 / 12428 MSPI0406S00092398 1.206167076 9.82E-09
NM_020070 IGLL1 immunoglobulin lambda-like polypeptide 1 chr22q11.23 0.38808208 6.59E-07 206660_at 2.610574287 0.003057996 1636 / 12428 MSPI0406S00959914 0.423224432 1.42E-07
NM_001114618 MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase chr5q35 0.384701429 8.39E-07 201126_s_at 1.525530592 7.09E-07 625 / 12428 MSPI0406S00302928 1.143800945 7.24E-25
NM_024490 ATP10A ATPase, class V, type 10A chr15q11.2 0.382751277 9.63E-07 214255_at 1.59806748 0.014398167 2212 / 12428 MSPI0406S00700799 1.267126035 6.67E-05
NM_023015 INTS3 integrator complex subunit 3 chr1q21.3 0.381436255 1.06E-06 202809_s_at 1.813676436 3.10E-06 702 / 12428 MSPI0406S00056245 0.886212724 3.39E-14
NM_014959 CARD8 caspase recruitment domain family, member 8 chr19q13.33 0.377982971 1.35E-06 204950_at 1.380491839 0.001206511 1418 / 12428 MSPI0406S00900053 0.773995765 0.000165481
NM_001236 CBR3 carbonyl reductase 3 chr21q22.2 0.376925754 1.45E-06 205379_at 2.11304127 0.000162991 1071 / 12428 MSPI0406S00945832 1.291893938 7.26E-14
NM_000048 ASL /// CRCP argininosuccinate lyase /// CGRP receptor component chr7cen-q11.2 /// chr7q11.21 0.374362047 1.73E-06 204608_at 1.492662423 0.000104703 1029 / 12428 MSPI0406S00374760 1.44668473 1.65E-17
NM_013233 STK39 serine threonine kinase 39 (STE20/SPS1 homolog, yeast) chr2q24.3 0.371662408 2.08E-06 202786_at 1.438391324 0.026352009 2542 / 12428 MSPI0406S00138625 0.549549834 0.000169237
NM_004840 ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 chrXq26.3 0.369650072 2.38E-06 209539_at 1.25044494 0.04718179 2935 / 12428 MSPI0406S01015291 0.634560965 0.01086548
NM_024734 CLMN calmin (calponin-like, transmembrane) chr14q32.13 0.368628494 2.55E-06 213839_at 1.514339651 0.026937916 2552 / 12428 MSPI0406S00689865 0.827668936 7.03E-10
NM_016021 UBE2J1 ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) chr6q15 0.367782621 2.70E-06 217823_s_at 1.672067415 3.85E-05 916 / 12428 MSPI0406S00330769 1.853753739 7.36E-12
NM_033386 MICALL1 MICAL-like 1 chr22q13.1-q13.2 0.364296428 3.41E-06 55081_at 1.42467043 6.43E-07 617 / 12428 MSPI0406S00969697 2.326604451 1.10E-21
NM_014666 CLINT1 clathrin interactor 1 chr5q33.3 0.361004772 4.23E-06 201768_s_at 1.175180405 0.046612975 2922 / 12428 MSPI0406S00292577 1.612916574 4.41E-12
NM_002452 NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 chr7p22 0.36090026 4.26E-06 204766_s_at 1.554890388 0.016130463 2280 / 12428 MSPI0406S00354667 1.051100579 1.58E-13
NM_015015 KDM4B lysine (K)-specific demethylase 4B chr19p13.3 0.354720907 6.37E-06 212496_s_at 1.792617037 1.07E-05 802 / 12428 MSPI0406S00865599 0.615375187 0.048242097
NM_000118 ENG endoglin chr9q33-q34.1 0.349033846 9.15E-06 201809_s_at 3.159064487 6.76E-11 292 / 12428 MSPI0406S00484935 1.023697398 5.72E-07
NM_003583 DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 chr12q15 0.346488648 1.07E-05 202969_at 1.640940988 8.34E-08 516 / 12428 MSPI0406S00618333 1.362966565 6.62E-24
NM_018656 SLC35E3 solute carrier family 35, member E3 chr12q15 0.345394494 1.15E-05 218988_at 5.701815729 3.00E-11 268 / 12428 MSPI0406S00618596 0.356591823 3.71E-05
NM_020185 DUSP22 dual specificity phosphatase 22 chr6p25.3 0.345121679 1.17E-05 218845_at 1.601469664 3.33E-08 480 / 12428 MSPI0406S00303444 1.50916082 4.23E-15
NM_001076787 TP53I11 tumor protein p53 inducible protein 11 chr11p11.2 0.344712073 1.20E-05 214667_s_at 1.726590916 0.004701088 1784 / 12428 MSPI0406S00562232 2.859652999 2.03E-26
NM_002800 PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) chr6p21.3 0.342306969 1.39E-05 204279_at 1.4764489 0.000942425 1373 / 12428 MSPI0406S00316938 0.726509549 0.037716302
NM_025159 CXorf21 chromosome X open reading frame 21 chrXp21.2 0.342182393 1.40E-05 220252_x_at 2.011897067 9.63E-06 794 / 12428 MSPI0406S00992365 1.534516056 4.26E-20
NM_002287 LAIR1 leukocyte-associated immunoglobulin-like receptor 1 chr19q13.4 0.339182859 1.68E-05 210644_s_at 1.484640091 0.004355335 1757 / 12428 MSPI0406S00906287 1.250865607 1.61E-08
NM_004288 CYTIP cytohesin 1 interacting protein chr2q11.2 0.338822375 1.72E-05 209606_at 1.769341119 0.000206778 1103 / 12428 MSPI0406S00136981 1.164641691 5.36E-11
NM_004232 SOCS6 suppressor of cytokine signaling 6 chr18q22.2 0.330677506 2.81E-05 206020_at 1.364480778 0.020571994 2392 / 12428 MSPI0406S00854096 0.677252424 0.000321145
NM_000246 CIITA class II, major histocompatibility complex, transactivator chr16p13 0.330129555 2.90E-05 205101_at 7.066132001 1.37E-33 9 / 12428 MSPI0406S00742469 0.962212668 1.31E-05
NM_005100 AKAP12 A kinase (PRKA) anchor protein 12 chr6q24-q25 0.329505144 3.01E-05 210517_s_at 4.550956372 2.04E-07 555 / 12428 MSPI0406S00342872 0.703003249 1.68E-10
NM_001946 DUSP6 dual specificity phosphatase 6 chr12q22-q23 0.328323572 3.22E-05 208892_s_at 2.392691377 1.39E-06 651 / 12428 MSPI0406S00621301 0.77929829 2.71E-10
NM_016121 KCTD3 potassium channel tetramerisation domain containing 3 chr1q41 0.326890095 3.51E-05 217894_at 1.739581225 2.46E-05 861 / 12428 MSPI0406S00074548 0.737598671 0.000468043
NM_003307 TRPM2 transient receptor potential cation channel, subfamily M, member 2 chr21q22.3 0.324507288 4.03E-05 205708_s_at 1.626474849 0.00019485 1092 / 12428 MSPI0406S00951558 1.39603692 4.92E-13
NM_005574 LMO2 LIM domain only 2 (rhombotin-like 1) chr11p13 0.322680056 4.48E-05 204249_s_at 1.520808558 0.009296691 2027 / 12428 MSPI0406S00559727 0.480361691 0.009957542
NM_025113 C13orf18 chromosome 13 open reading frame 18 chr13q14.13 0.318613716 5.65E-05 44790_s_at 2.391793334 0.000712026 1314 / 12428 MSPI0406S00652217 0.780862268 4.35E-12
NM_005907 MAN1A1 mannosidase, alpha, class 1A, member 1 chr6q22 0.316924151 6.21E-05 221760_at 2.985032583 2.90E-05 881 / 12428 MSPI0406S00336211 0.842920521 7.69E-06
NM_000389 CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) chr6p21.2 0.313899496 7.36E-05 202284_s_at 4.806850531 4.12E-15 145 / 12428 MSPI0406S00319805 0.51023796 0.003676786
NM_014795 ZEB2 zinc finger E-box binding homeobox 2 chr2q22.3 0.310400018 8.94E-05 203603_s_at 2.873298801 3.26E-16 130 / 12428 MSPI0406S00135007 0.7129151 5.58E-06
NM_006932 SMTN smoothelin chr22q12.2 0.308953214 9.68E-05 207390_s_at 1.765409708 0.00071505 1318 / 12428 MSPI0406S00964990 1.492592204 8.18E-30
NM_000581 GPX1 glutathione peroxidase 1 chr3p21.3 0.307907171 0.000102454 200736_s_at 2.270121286 3.05E-10 335 / 12428 MSPI0406S00177627 0.354647735 0.017390421
NM_001024808 BCL7A B-cell CLL/lymphoma 7A chr12q24.13 0.306139746 0.0001128 203795_s_at 1.401908198 0.015273881 2246 / 12428 MSPI0406S00634978 0.724395988 1.24E-05
NM_001013694 SRRD SRR1 domain containing chr22q12.1 0.301101333 0.000147898 213608_s_at 1.391878927 0.006635509 1909 / 12428 MSPI0406S00962017 0.921590848 0.001085247
NM_000101 CYBA cytochrome b-245, alpha polypeptide chr16q24 0.28890605 0.000279254 203028_s_at 1.624432281 0.000395217 1212 / 12428 MSPI0406S00778836 0.24396684 0.022914455
NM_001321 CSRP2 cysteine and glycine-rich protein 2 chr12q21.1 0.286751616 0.000311528 207030_s_at 7.98029658 5.00E-25 50 / 12428 MSPI0406S00619987 0.274788427 0.048862742
NM_153045 C9orf91 chromosome 9 open reading frame 91 chr9q32 0.286496115 0.000315576 221865_at 1.396426365 1.82E-06 664 / 12428 MSPI0406S00479393 0.477025071 0.037400064
NM_001011667 CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 chr8q12.1 0.285072797 0.000339036 218642_s_at 1.745599599 1.85E-07 548 / 12428 MSPI0406S00429545 0.499564444 1.64E-05
NM_005239 ETS2 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) chr21q22.3|21q22.2 0.284230186 0.000353676 201328_at 2.048849636 2.89E-05 879 / 12428 MSPI0406S00947260 0.503932744 0.013394919
NM_001134380 TBC1D5 TBC1 domain family, member 5 chr3p24.3 0.282191202 0.000391557 201813_s_at 1.664165097 0.002951215 1620 / 12428 MSPI0406S00168751 0.335265377 0.02047252
NM_001005743 NUMB numb homolog (Drosophila) chr14q24.3 0.280855133 0.000418378 209073_s_at 1.36676929 0.000201288 1095 / 12428 MSPI0406S00681677 1.268430511 7.36E-06
NM_000788 DCK deoxycytidine kinase chr4q13.3-q21.1 0.280738306 0.000420802 203302_at 1.27141644 0.020557171 2390 / 12428 MSPI0406S00234064 1.070964167 2.42E-05
NM_001130480 VRK2 vaccinia related kinase 2 chr2p16-p15 0.28044082 0.000427034 205126_at 1.416757484 3.10E-05 895 / 12428 MSPI0406S00108816 1.133484013 5.66E-06
NM_003693 SCARF1 scavenger receptor class F, member 1 chr17p13.3 0.279802362 0.000440698 206995_x_at 1.650075363 5.39E-05 957 / 12428 MSPI0406S00782706 0.50745827 0.000569146
NM_004271 LY86 lymphocyte antigen 86 chr6p25.1 0.275432554 0.000545617 205859_at 2.89985238 1.44E-12 224 / 12428 MSPI0406S00306424 0.745682061 2.16E-08
NM_000536 RAG2 recombination activating gene 2 chr11p13 0.274104719 0.000581795 215117_at 1.616966282 0.026309218 2541 / 12428 MSPI0406S00560646 1.973682863 1.67E-08
NM_001115156 GDI2 GDP dissociation inhibitor 2 chr10p15 0.27378458 0.000590842 200009_at 1.376976178 5.37E-05 956 / 12428 MSPI0406S00500320 0.638707581 2.39E-07
NM_001060 TBXA2R thromboxane A2 receptor chr19p13.3 0.268603277 0.000756501 336_at 1.360612736 0.02852732 2591 / 12428 MSPI0406S00863537 0.628998813 9.59E-10
NM_001159291 MICAL1 microtubule associated monoxygenase, calponin and LIM domain containing 1 chr6q21 0.268186256 0.000771538 218376_s_at 1.968154383 1.22E-05 813 / 12428 MSPI0406S00334252 0.339933617 0.000523945
NM_000129 F13A1 coagulation factor XIII, A1 polypeptide chr6p25.3-p24.3 0.268105667 0.000774475 203305_at 2.265907851 8.61E-05 999 / 12428 MSPI0406S00306365 0.270630466 6.35E-05
NM_025076 UXS1 UDP-glucuronate decarboxylase 1 chr2q12.2 0.266526341 0.000834154 219675_s_at 1.944698597 1.25E-14 157 / 12428 MSPI0406S00123125 0.653339274 7.65E-06
NM_019891 ERO1LB ERO1-like beta (S. cerevisiae) chr1q42.2-q43 0.266385916 0.000839659 220012_at 1.918051497 1.11E-05 807 / 12428 MSPI0406S00082353 2.245745137 2.60E-28
NM_002567 PEBP1 phosphatidylethanolamine binding protein 1 chr12q24.23 0.263799723 0.000947213 210825_s_at 1.674495856 8.62E-08 519 / 12428 MSPI0406S00632233 0.582505475 0.00101558
NM_002484 NUBP1 nucleotide binding protein 1 (MinD homolog, E. coli) chr16p13.13 0.262012099 0.001028788 203978_at 1.520349159 2.93E-11 267 / 12428 MSPI0406S00742355 0.224757563 0.03252636
NM_016217 HECA headcase homolog (Drosophila) chr6q23-q24 0.260528651 0.001101317 218603_at 1.435611762 0.00079339 1338 / 12428 MSPI0406S00339829 2.473367118 1.02E-24
NM_001031628 SMAGP small trans-membrane and glycosylated protein chr12q13.13 0.258984246 0.001181775 209679_s_at 1.752648167 0.00323433 1653 / 12428 MSPI0406S00612442 0.882855263 0.00809589
NM_004568 SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 chr6p25 0.258574175 0.001204023 211474_s_at 2.266737249 7.13E-07 626 / 12428 MSPI0406S00304760 0.636261579 4.99E-05
NM_004779 CNOT8 CCR4-NOT transcription complex, subunit 8 chr5q31-q33 0.257582449 0.001259422 202164_s_at 1.203569921 0.015287712 2251 / 12428 MSPI0406S00291793 0.459680775 0.032533889
NM_006621 AHCYL1 adenosylhomocysteinase-like 1 chr1p13.2 0.257467741 0.001265978 200850_s_at 1.163690775 0.026289365 2538 / 12428 MSPI0406S00049370 0.93694802 5.51E-08
NM_000252 MTM1 myotubularin 1 chrXq28 0.257302553 0.001275473 36920_at 1.744369463 4.22E-06 718 / 12428 MSPI0406S01017993 1.666996297 1.34E-11
NM_015073 SIPA1L3 signal-induced proliferation-associated 1 like 3 chr19q13.13 0.256070594 0.00134837 213600_at 1.631374054 0.000113847 1042 / 12428 MSPI0406S00890540 0.395536123 0.00868016
NM_001156474 CCDC81 coiled-coil domain containing 81 chr11q14.2 0.252975367 0.001548616 220389_at 2.527969888 1.19E-05 809 / 12428 MSPI0406S00581723 1.314019403 2.18E-07
NM_004579 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 chr11q13 0.251210311 0.001674596 204936_at 1.392412861 0.023547733 2461 / 12428 MSPI0406S00569922 1.921360159 1.03E-43
NR_026779 C14orf139 chromosome 14 open reading frame 139 chr14q32.13 0.249337272 0.001818434 219563_at 3.882360718 8.24E-23 69 / 12428 MSPI0406S00689927 0.837285497 0.00142176
NM_002116 HLA-A major histocompatibility complex, class I, A chr6p21.3 0.245563698 0.002142875 215313_x_at 1.505219591 0.000119976 1046 / 12428 MSPI0406S00314925 0.599273749 0.003292916
NM_001664 RHOA ras homolog gene family, member A chr3p21.3 0.243693351 0.002322423 200059_s_at 1.286814157 0.000971211 1384 / 12428 MSPI0406S00177688 0.716111045 4.56E-07
NM_006577 B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 chr2p15 0.241869838 0.002510499 219326_s_at 1.456948814 0.001553378 1470 / 12428 MSPI0406S00110095 0.694769654 1.16E-07
NM_014240 LIMD1 LIM domains containing 1 chr3p21.3 0.241613155 0.002538053 218850_s_at 1.446018887 0.023303493 2451 / 12428 MSPI0406S00175023 1.13051494 5.26E-05
NM_001098426 SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 chr17q23-q24 0.241432929 0.002557563 201827_at 1.380291621 3.03E-06 698 / 12428 MSPI0406S00819275 1.504715315 3.59E-24
NM_012154 EIF2C2 Eukaryotic translation initiation factor 2C, 2 chr8q24 0.235116703 0.003333209 213310_at 1.307458219 0.010861589 2095 / 12428 MSPI0406S00446999 1.389904445 5.01E-06
NM_002167 ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein chr1p36.13-p36.12 0.230177792 0.004081106 207826_s_at 4.283329371 6.19E-08 504 / 12428 MSPI0406S00020688 0.774845681 8.02E-11
NM_000077 CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) chr9p21 0.228757874 0.004322401 209644_x_at 1.723245148 0.000479606 1243 / 12428 MSPI0406S00456709 0.535208968 0.000779916
NM_003288 TPD52L2 tumor protein D52-like 2 chr20q13.2-q13.3 0.22777089 0.00449759 201379_s_at 1.673195631 2.93E-05 885 / 12428 MSPI0406S00939698 0.886207548 2.94E-10
NM_025149 ACSF2 acyl-CoA synthetase family member 2 chr17q21.33 0.22240168 0.00556696 218844_at 1.388572647 0.000573519 1282 / 12428 MSPI0406S00813773 1.156716803 5.66E-12
NM_000521 HEXB hexosaminidase B (beta polypeptide) chr5q13 0.220856507 0.00591419 201944_at 1.746546276 8.11E-12 250 / 12428 MSPI0406S00273755 0.639588041 2.36E-11
NM_005319 HIST1H1C histone cluster 1, H1c chr6p21.3 0.219388747 0.006261789 209398_at 2.04080405 0.000537886 1262 / 12428 MSPI0406S00313168 1.837618294 6.53E-11
NM_001142546 LUZP1 leucine zipper protein 1 chr1p36 0.214622458 0.007519494 221831_at 1.656359523 0.001132072 1407 / 12428 MSPI0406S00020371 0.416538753 0.000917125
NM_001031714 INF2 inverted formin, FH2 and WH2 domain containing chr14q32.33 0.21429007 0.00761504 218144_s_at 1.22201382 0.0276256 2564 / 12428 MSPI0406S00696642 0.811587417 1.01E-09
NM_017807 OSGEP O-sialoglycoprotein endopeptidase chr14q11.2 0.213650909 0.007801802 209450_at 1.226304616 0.010063488 2056 / 12428 MSPI0406S00667526 0.769502026 0.000326212
NM_030797 FAM49A family with sequence similarity 49, member A chr2p24.2 0.213518283 0.00784106 209683_at 4.755367787 1.99E-18 95 / 12428 MSPI0406S00095620 0.289166466 0.0036918
NM_003521 HIST1H2BM histone cluster 1, H2bm chr6p22-p21.3 0.21243609 0.008168001 208515_at 1.393025165 0.005815752 1871 / 12428 MSPI0406S00314135 0.701377659 1.17E-06
NM_000594 TNF tumor necrosis factor (TNF superfamily, member 2) chr6p21.3 0.211551256 0.008444235 207113_s_at 1.311036679 0.038541828 2779 / 12428 MSPI0406S00315947 2.765630758 1.79E-46
NM_001005862 ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) chr17q11.2-q12|17q21.1 0.211404057 0.008490982 216836_s_at 1.43364855 0.011573742 2120 / 12428 MSPI0406S00805393 0.358992892 0.030593062
NM_012135 FAM50B family with sequence similarity 50, member B chr6p25-pter 0.207153823 0.009943399 205775_at 1.313117497 0.014959849 2234 / 12428 MSPI0406S00305367 0.645381603 0.000923222
NM_004813 PEX16 peroxisomal biogenesis factor 16 chr11p11.2 0.206745161 0.010093977 49878_at 1.17167416 0.003922244 1718 / 12428 MSPI0406S00562783 1.932339879 2.67E-22
NM_001894 CSNK1E casein kinase 1, epsilon chr22q13.1 0.206589081 0.010152015 202332_at 1.297767357 0.018118575 2330 / 12428 MSPI0406S00970221 1.677622928 1.29E-07
NM_003906 MCM3AP minichromosome maintenance complex component 3 associated protein chr21q22.3 0.205946721 0.010393985 215582_x_at 1.202414991 0.020091231 2374 / 12428 MSPI0406S00953548 1.431235158 2.25E-10
NM_013401 RAB3IL1 RAB3A interacting protein (rabin3)-like 1 chr11q12-q13.1 0.203755005 0.011258252 219579_at 1.212573589 0.049750563 2974 / 12428 MSPI0406S00567424 1.735863604 8.55E-18
NM_004533 MYBPC2 myosin binding protein C, fast type chr19q13.33 0.203629483 0.011309609 206394_at 1.893012816 0.002874995 1612 / 12428 MSPI0406S00902859 0.644298638 1.28E-08
NM_001066 TNFRSF1B tumor necrosis factor receptor superfamily, member 1B chr1p36.3-p36.2 0.203347008 0.011425936 203508_at 1.616522449 0.011742296 2127 / 12428 MSPI0406S00011871 0.318001131 0.001402174
NM_001018078 FPGS folylpolyglutamate synthase chr9q34.1 0.196828914 0.014418459 202945_at 1.424250004 0.000239375 1129 / 12428 MSPI0406S00484872 1.574719014 2.73E-10
NM_000116 TAZ tafazzin chrXq28 0.196675304 0.014496551 37278_at 1.200708107 0.012315914 2151 / 12428 MSPI0406S01020170 0.817358362 8.75E-06
NM_005475 SH2B3 SH2B adaptor protein 3 chr12q24 0.196470394 0.014601296 203320_at 1.310307143 0.037438006 2759 / 12428 MSPI0406S00628445 1.040524911 8.26E-18
NM_001040455 SIDT2 SID1 transmembrane family, member 2 chr11q23.3 0.192942184 0.016511285 56256_at 1.35448564 0.001274546 1431 / 12428 MSPI0406S00587902 0.135615433 0.033429236
NM_173354 SIK1 salt-inducible kinase 1 chr21q22.3 0.187324762 0.020000862 208078_s_at 2.183198977 0.002000165 1524 / 12428 MSPI0406S00950474 1.920576503 9.02E-22
NM_002528 NTHL1 nth endonuclease III-like 1 (E. coli) chr16p13.3 0.186475322 0.020580485 209731_at 1.327875294 0.017048523 2298 / 12428 MSPI0406S00736133 0.891917693 2.84E-10
NM_031310 PLVAP plasmalemma vesicle associated protein chr19p13.2 0.185876323 0.020997884 221529_s_at 1.84368721 0.004935926 1797 / 12428 MSPI0406S00878837 0.262320647 0.000644182
NM_013449 BAZ2A bromodomain adjacent to zinc finger domain, 2A chr12q24.3-qter 0.184208137 0.022199029 201354_s_at 1.690105904 1.67E-05 835 / 12428 MSPI0406S00615771 0.673145895 3.11E-14
NM_002574 PRDX1 peroxiredoxin 1 chr1p34.1 0.183893962 0.022431745 208680_at 2.0365508 3.01E-08 474 / 12428 MSPI0406S00034956 0.798139131 0.000547815
NM_021813 BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 chr6q15 0.183885154 0.022438299 221234_s_at 4.223062857 7.31E-16 132 / 12428 MSPI0406S00331128 0.577268988 0.038563175
NM_004440 EPHA7 EPH receptor A7 chr6q16.1 0.183120038 0.023013982 206852_at 2.286603813 0.000665911 1304 / 12428 MSPI0406S00331432 0.650586726 1.49E-06
NM_017999 RNF31 ring finger protein 31 chr14q11.2 0.182865436 0.023208344 220788_s_at 1.230987018 0.031332914 2638 / 12428 MSPI0406S00669481 0.303620512 0.013129252
NM_002118 HLA-DMB major histocompatibility complex, class II, DM beta chr6p21.3 0.181686857 0.024126553 203932_at 4.800992389 1.50E-23 61 / 12428 MSPI0406S00316958 0.171606264 0.03638297
NM_006889 CD86 CD86 molecule chr3q21 0.181116026 0.024582374 210895_s_at 1.522006567 0.017517246 2312 / 12428 MSPI0406S00192518 2.328456983 6.05E-30
NM_002526 NT5E 5'-nucleotidase, ecto (CD73) chr6q14-q21 0.17782233 0.027359289 203939_at 3.048756469 5.93E-05 969 / 12428 MSPI0406S00329870 0.636229752 2.20E-08
NM_006703 NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 chr6p21.2 0.170469435 0.034538217 221579_s_at 1.30863779 0.000557071 1275 / 12428 MSPI0406S00318277 1.103693991 7.85E-06
NR_024448 LOC91316 glucuronidase, beta/ immunoglobulin lambda-like polypeptide 1 pseudogene chr22q11.23 0.169942434 0.035108917 213502_x_at 1.391887789 0.017982179 2327 / 12428 MSPI0406S00960029 0.667382628 3.69E-17
NM_000993 RPL31 ribosomal protein L31 chr2q11.2 0.166463662 0.03907955 221593_s_at 1.334545612 0.005138094 1821 / 12428 MSPI0406S00121365 0.571797519 0.001673437
NM_003900 SQSTM1 sequestosome 1 chr5q35 0.161954946 0.044781471 201471_s_at 1.243822834 0.005189052 1824 / 12428 MSPI0406S00302042 1.128336905 6.69E-12
NM_001025108 AFF3 AF4/FMR2 family, member 3 chr2q11.2-q12 0.160053943 0.047385679 205735_s_at 1.49535095 0.024169462 2472 / 12428 MSPI0406S00120890 2.733149169 6.60E-28
NM_152288 ORAI3 ORAI calcium release-activated calcium modulator 3 chr16p11.2 0.159817909 0.047717653 221864_at 1.335819229 0.005724588 1866 / 12428 MSPI0406S00755297 0.328251624 0.016790111
NM_001114634 PLAG1 pleiomorphic adenoma gene 1 chr8q12 0.159039942 0.048825567 205372_at 1.713550325 0.006084846 1882 / 12428 MSPI0406S00429545 0.499564444 1.64E-05
NM_021008 DEAF1 deformed epidermal autoregulatory factor 1 (Drosophila) chr11p15.5 0.158696892 0.049320859 209407_s_at 1.28918836 0.022552313 2439 / 12428 MSPI0406S00548885 1.373425653 7.96E-29