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Kriwacki Lab: Supplemental Data

NPM1 Exhibits Structural and Dynamic Heterogeneity upon Phase Separation with the p14ARF Tumor Suppressor. Journal of Magnetic Resonance. (2019)

Authors and Affiliations:

Eric Gibbs
Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place Memphis, Tennessee 38105, USA; Memphis, Tennessee 38112, USA; Email: eric.gibbs@stjude.org

Richard W. Kriwacki
Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place Memphis, Tennessee 38105, USA; Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Sciences Center, 910 Madison Avenue, Memphis, Tennessee 38163, USA; Email: richard.kriwacki@stjude.org

Barbara Perrone
Bruker Switzerland AG, Industriestrasse 26, CH-8117 Fällanden, Switzerland

Alia Hassan
Bruker Switzerland AG, Industriestrasse 26, CH-8117 Fällanden, Switzerland

Rainer Kümmerle
Bruker Switzerland AG, Industriestrasse 26, CH-8117 Fällanden, Switzerland


Filename Size Description
NPM1_2PERCENT_DMSO_TROSY-HSQC.ucsf 4.19 MB TROSY-HSQC of [2H,15N]-NPM1, collected in the presence of 2% DMSO
NPM1_TROSY-HSQC.ucsf 4.19 MB TROSY-HSQC of [2H,15N]-NPM1
p14ARF_NPM1_DP_CC-DARR.ucsf 33.54 MB CC-DARR spectrum of [U13C,U15N]-NPM1-p14ARF condensed phase
p14ARF_NPM1_DP_INEPT-TOBSY.ucsf 8.39 MB INEPT-TOBSY spectrum of [U13C,U15N]-NPM1-p14ARF condensed phase
p14ARF_NPM1_DP_NCA.ucsf 33.55 MB NCA spectrum of [U13C,U15N]-NPM1-p14ARF condensed phase
p14ARF_NPM1_DP_NCACX2D.ucsf 2.09 MB 2D NCACX spectrum of [U13C,U15N]-NPM1-p14ARF condensed phase
p14ARF_NPM1_DP_NCACX3D.ucsf 268.44 MB 3D NCACX spectrum of [U13C,U15N]-NPM1-p14ARF condensed phase
p14ARF_NPM1_DP_NCO.ucsf 8.39 MB NCO spectrum of [U13C,U15N]-NPM1-p14ARF condensed phase
p14ARF_NPM1_DP_NCOCX3D.ucsf 1.07 GB 3D NCOCX spectrum of [U13C,U15N]-NPM1-p14ARF condensed phase


Exploring Relationships between the Density of Charged Tracts within Disordered Regions and Phase Separation

Ramiz Somjee
Department of Structural Biology, St. Jude Children’s Research Hospital, 262 Danny Thomas Place Memphis, Tennessee 38105, USA;
Department of Chemistry, Rhodes College, 2000 North Parkway
Memphis, Tennessee 38112, USA;
Email: ramiz.somjee@stjude.org

Diana M. Mitrea
Department of Structural Biology, St. Jude Children’s Research Hospital, 262 Danny Thomas Place Memphis, Tennessee 38105, USA
Email: diana.mitrea@stjude.org

Richard W. Kriwacki
Department of Structural Biology, St. Jude Children’s Research Hospital, 262 Danny Thomas Place Memphis, Tennessee 38105, USA;
Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Sciences Center, 910 Madison Avenue, Memphis, Tennessee 38163, USA;
Email: richard.kriwacki@stjude.org