Acute Lymphoblastic Leukemia  
APPLICATIONS / DATABASESSUPPLEMENTAL DATAFACULTYMIRROR SITESCOLLABORATIVE PROJECTSDEPARTMENTS

BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
Charles G. Mullighan, Christopher B. Miller, Letha A. Phillips, Ina Radtke, James Dalton, Jing Ma, Deborah White, Timothy P. Hughes, Michelle M. Le Beau, Ching-Hon Pui, Mary V. Relling, Sheila A. Shurtleff and James R. Downing
Nature 2008

Expression of the outcome predictor in acute leukemia 1 (OPAL1) gene is not an independent prognostic factor in patients treated according to COALL or St Jude protocols
Holleman A, den Boer ML, Cheok MH, Kazemier KM, Pei D, Downing JR, Janka-Schaub GE, Gobel U, Graubner UB, Pui CH, Evans WE, Pieters R.
Blood. 2006 Sep 15;108(6): 1984-90.

Identification of genes associated with chemotherapy cross-resistance and treatment response in childhood acute lymphoblastic leukemia.
Sanne Lugthart, Meyling H. Cheok, Monique L. den Boer, Wenjian Yang, Amy Holleman, Cheng Cheng, Ching-Hon Pui, Mary V. Relling, Gritta E. Janka-Schaub, Rob Pieters, William E. Evans

Gene-expression patterns in drug resistant acute lymphoblastic leukemia cells and response to treatment.
Amy Holleman, Meyling H. Cheok, Monique L. den Boer, Wenjian Yang, Anjo J.P. Veerman, Karin M. Kazemier, Deqing Pei, Cheng Cheng, Ching-Hon Pui, Mary V. Relling, Gritta E. Janka-Schaub, Rob Pieters, and William E. Evans
New England Journal of Medicine 2004; 351

Classification of Pediatric Acute Lymphoblastic Leukemia by Gene Expression Profile
Mary E. Ross, Xiadong Zhou, Guangchun Song, Sheila A. Shurtleff, Kevin Girtman, W. Kent Williams, Hsi-Che Liu, Rami Mahfouz, Susana C. Raimondi, Noel Lenny, Anami Patel, James R. Downing
to determine whether prediction of host range or pandemic potential is possible.
Blood 2003

Treatment-specific Changes in Gene Expression Discriminate in vivo Drug
response in Human Leukemia Cells

Meyling H. Cheok, Wenjian Yang, Ching Hon Pui, James R. Downing, CHeng Cheng, Clayton W. Naeve, Mary V. Relling, William E. Evans
Nature Genetics 2003

Pediatric Lymphoblastic Leukemia by Gene Expression Profiling
Eng-Juh Yeoh, Mary E. Ross, Shelia A. Shurtleff, W. Kent Williams, Divyen Patel, Rami Mahfouz, Fred G. Behm, Susana C. Raimondi, Mary V. Relling, Anami Patel, Cheng Cheng, Dario Campana, Dawn Wilkins, Xiaodong Zhou, Jinyan Li, Huiqing Liu, Ching-Hon Pui, William E. Evans, Clayton Naeve, Limsoon Wong, James R. Downing
Cancer Cell Volume 2002 1:133-143

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
Charles G. Mullighan, Salil Goorha, Ina Radtke, Christopher B. Miller, Elaine Coustan-Smith, James D. Dalton, Kevin Girtman, Susan Mathew, Jing Ma, Stanley B. Pounds, Xiaoping Su, Ching-Hon Pui, Mary V. Relling, William E. Evans, Sheila A. Shurtleff and James R. Downing