Labs
Mead lab

Publications

BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
Charles G. Mullighan, Christopher B. Miller, Letha A. Phillips, Ina Radtke, James Dalton, Jing Ma, Deborah White, Timothy P. Hughes, Michelle M. Le Beau, Ching-Hon Pui, Mary V. Relling, Sheila A. Shurtleff and James R. Downing
Nature 2008

Pediatric Lymphoblastic Leukemia by Gene Expression Profiling
(2002) Cancer Cell Volume 1:133-143
Eng-Juh Yeoh, Mary E. Ross, Shelia A. Shurtleff, W. Kent Williams, Divyen Patel, Rami Mahfouz, Fred G. Behm, Susana C. Raimondi, Mary V. Relling, Anami Patel, Cheng Cheng, Dario Campana, Dawn Wilkins, Xiaodong Zhou, Jinyan Li, Huiqing Liu, Ching-Hon Pui, William E. Evans, Clayton Naeve, Limsoon Wong, James R. Downing

Treatment-specific Changes in Gene Expression Discriminate in vivo Drug
response in Human Leukemia Cells
(2003) Nature Genetics
Meyling H. Cheok, Wenjian Yang, Ching Hon Pui, James R. Downing, Cheng Cheng, Clayton W. Naeve, Mary V. Relling, William E. Evans

Classification of Pediatric Acute Lymphoblastic Leukemia by Gene Expression Profile
Mary E. Ross, Xiadong Zhou, Guangchun Song, Sheila A. Shurtleff, Kevin Girtman, W. Kent Williams, Hsi-Che Liu, Rami Mahfouz, Susana C. Raimondi, Noel Lenny, Anami Patel, James R. Downing Blood 2003

Gene Expression Profiling of Pediatric Acute Myelogenous Leukemia
Mary E. Ross, Rami Mahfouz, Mihaela Onciu, Hsi-Che Liu, Xiadong Zhou, Guangchun Song, Shelia A. Shurtleff, Stanley Pounds, Cheng Cheng, Jing Ma, Raul C. Riberiro, Jeffrey E. Rubnitz, Kevin Girtman, W. Kent Williams, Susana C. Raimondi, Der-Chemg Liang, Lee-Yung Shih, CHing-Hon Pui & James R. Downing Blood 2004

Expression of the outcome predictor in acute leukemia 1 (OPAL1) gene is not an independent prognostic factor in patients treated according to COALL or St Jude protocols.
Holleman A, den Boer ML, Cheok MH, Kazemier KM, Pei D, Downing JR, Janka-Schaub GE, Gobel U, Graubner UB, Pui CH, Evans WE, Pieters R.
Blood. 2006 Sep 15;108(6): 1984-90.