APPLICATIONS / DATABASESSUPPLEMENTAL DATAFACULTYMIRROR SITESCOLLABORATIVE PROJECTSDEPARTMENTS

 


Section III
continued...



Table S7.
Top 100 chi-square probe sets selected for T-ALL in decision tree format

 

U133
probe set

Gene description

Symbol

Location

GenBank Reference

Chi-square

T-ALL above/below mean

Fold change

old or new

1

201137_s_at

major histocompatibility complex, class II, DP beta 1

HLA-DPB1

6p21.3

NM_002121.1

100.0

Below

21.0

old

2

202113_s_at

sorting nexin 2

SNX2

5q23

AF043453.1

100.0

Below

4.2

old

3

202114_at

sorting nexin 2

SNX2

5q23

NM_003100.1

100.0

Below

4.6

old

4

203675_at

nucleobindin 2

NUCB2

11p15.1-p14

NM_005013.1

100.0

Above

3.6

old

5

204670_x_at

major histocompatibility complex, class II, DR beta 3

HLA-DRB3

6p21.3

NM_002125.1

100.0

Below

13.4

old

6

205297_s_at

CD79B antigen (immunoglobulin-associated beta)

CD79B

17q23

NM_000626.1

100.0

Below

23.3

old

7

205456_at

CD3E antigen, epsilon polypeptide (TiT3 complex)

CD3E

11q23

NM_000733.1

100.0

Above

20.7

old

8

206398_s_at

CD19 antigen

CD19

16p11.2

NM_001770.1

100.0

Below

5693.6

old

9

208306_x_at

major histocompatibility complex, class II, DR beta 4

HLA-DRB4

6p21.3

NM_021983.2

100.0

Below

8.3

old

10

208894_at

major histocompatibility complex, class II, DR alpha

HLA-DRA

6p21.3

M60334.1

100.0

Below

20.9

old

11

209312_x_at

major histocompatibility complex, class II, DR beta 1

HLA-DRB1

6p21.3

U65585.1

100.0

Below

12.6

old

12

209619_at

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

CD74

5q32

K01144.1

100.0

Below

15.1

old

13

210116_at

SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome)

SH2D1A

Xq25-q26

AF072930.1

100.0

Above

150.7

old

14

210982_s_at

major histocompatibility complex, class II, DR alpha

HLA-DRA

6p21.3

M60333.1

100.0

Below

23.4

old

15

211990_at

major histocompatibility complex, class II, DP alpha 1

HLA-DPA1

6p21.3

M27487.1

100.0

Below

19.6

old

16

211991_s_at

major histocompatibility complex, class II, DP alpha 1

HLA-DPA1

6p21.3

M27487.1

100.0

Below

24.5

old

17

213539_at

CD3D antigen, delta polypeptide (TiT3 complex)

CD3D

11q23

NM_000732.1

100.0

Above

35.7

old

18

214049_x_at

CD7 antigen (p41)

CD7

17q25.2-q25.3

AI829961

100.0

Above

312.2

old

19

214551_s_at

CD7 antigen (p41)

CD7

17q25.2-q25.3

NM_006137.2

100.0

Above

228.1

old

20

217147_s_at

T-cell receptor interacting molecule

TRIM

3q13

AJ240085.1

100.0

Above

42.6

new

21

217478_s_at

MHC, class IIa, HLA-DMA

HLA-DMA

 

X76775

100.0

Below

11.9

old

22

221969_at

paired box gene 5 (B-cell lineage specific activator protein)

PAX5

9p13

BF510692

100.0

Below

3922.0

new

23

227646_at

early B-cell factor

EBF

5q34

BG435302

100.0

Below

85.0

new

24

229487_at

cDNA FLJ39389 fis

FLJ39389

5

W73890

100.0

Below

7685.7

new

25

229838_at

cDNA FLJ39156 fis

FLJ39156

 

AI377271

100.0

Above

12.7

old

26

232204_at

early B-cell factor

EBF

5q34

AF208502.1

100.0

Below

7129.1

new

27

203965_at

ubiquitin specific protease 20

USP20

9q34.12-q34.13

NM_006676.1

91.3

Above

9.0

old

28

204891_s_at

lymphocyte-specific protein tyrosine kinase

LCK

1p34.3

NM_005356.1

91.3

Above

13.8

old

29

205255_x_at

transcription factor 7 (T-cell specific, HMG-box)

TCF7

5q31.1

NM_003202.1

91.3

Above

8.4

old

30

207655_s_at

B-cell linker

BLNK

10q23.2-q23.33

NM_013314.1

91.3

Below

103.2

old

31

209771_x_at

CD24 antigen (small cell lung carcinoma cluster 4 antigen)

CD24

6q21

AA761181

91.3

Below

40.1

old

32

211796_s_at

T cell receptor beta locus

TRB

7q34

AF043179.1

91.3

Above

20.7

old

33

213792_s_at

insulin receptor

INSR

19p13.3-p13.2

AA485908

91.3

Below

8.0

old

34

215193_x_at

major histocompatibility complex, class II, DR beta 3

HLA-DRB3

6p21.3

AJ297586.1

91.3

Below

12.1

old

35

216379_x_at

KIAA1919 protein

KIAA1919

6q22.1

AK000168.1

91.3

Below

44.0

old

36

219191_s_at

bridging integrator 2

BIN2

12q13

NM_016293.1

91.3

Above

271.0

new

37

219563_at

hypothetical protein FLJ21276

FLJ21276

14q32.2

NM_024633.1

91.3

Below

5.8

new

38

219724_s_at

KIAA0748 gene product

KIAA0748

12q12

NM_014796.1

91.3

Above

11.6

new

39

221750_at

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)

HMGCS1

5p14-p13

BG035985

91.3

Above

3.4

new

40

226157_at

cDNA FLJ39131 fis

FLJ39131

3

AI569747

91.3

Above

4.4

old

41

226496_at

hypothetical protein FLJ22611

FLJ22611

9p11.1

BG291039

91.3

Below

7.6

new

42

266_s_at

CD24 antigen (small cell lung carcinoma cluster 4 antigen)

CD24

6q21

L33930

91.3

Below

69.7

old

43

39318_at

T-cell leukemia/lymphoma 1A

TCL1A

14q32.1

X82240

91.3

Below

367.4

old

44

204214_s_at

RAB32, member RAS oncogene family

RAB32

6q24.3

NM_006834.1

90.6

Above

127.9

new

45

204777_s_at

mal, T-cell differentiation protein

MAL

2cen-q13

NM_002371.2

90.6

Above

96.8

old

46

204890_s_at

lymphocyte-specific protein tyrosine kinase

LCK

1p34.3

U07236.1

90.6

Above

18.6

old

47

205049_s_at

CD79A antigen (immunoglobulin-associated alpha)

CD79A

19q13.2

NM_001783.1

90.6

Below

11.4

old

48

205254_x_at

transcription factor 7 (T-cell specific, HMG-box)

TCF7

5q31.1

AW027359

90.6

Above

352.0

old

49

205504_at

Bruton agammaglobulinemia tyrosine kinase

BTK

Xq21.33-q22

NM_000061.1

90.6

Below

6.6

old

50

210915_x_at

T cell receptor beta locus

TRB

7q34

M15564.1

90.6

Above

15.9

old

51

211211_x_at

SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome)

SH2D1A

Xq25-q26

AF100542.1

90.6

Above

1963.5

old

52

213830_at

T cell receptor delta locus

TRD

14q11.2

AW007751

90.6

Above

7411.2

old

53

216191_s_at

T cell receptor delta locus

TRD

14q11.2

X72501.1

90.6

Above

253.7

old

54

217143_s_at

T cell receptor delta locus

TRD

14q11.2

X06557.1

90.6

Above

151.9

old

55

219528_s_at

B-cell CLL/lymphoma 11B (zinc finger protein)

BCL11B

14q32.31-q32.32

NM_022898.1

90.6

Above

11.6

new

56

220418_at

ubiquitin associated and SH3 domain containing, A

UBASH3A

21q22.3

NM_018961.1

90.6

Above

759.3

new

57

222895_s_at

B-cell CLL/lymphoma 11B (zinc finger protein)

BCL11B

14q32.31-q32.32

AA918317

90.6

Above

11.7

new

58

223553_s_at

hypothetical protein FLJ22570

FLJ22570

5q35.3

BC004564.1

90.6

Below

6.1

new

59

225090_at

HRD1 protein

HRD1

11q12

AA844682

90.6

Below

3.6

new

60

226459_at

Homo sapiens gastric cancer-related protein GCYS-20 (gcys-20) mRNA, complete cds

   

AW575754

90.6

Below

10.7

new

61

228314_at

cDNA FLJ37485 fis

FLJ37485

 

BE877357

90.6

Below

4.7

new

62

201384_s_at

membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125)

M17S2

17q21.1

NM_005899.1

83.8

Above

3.3

new

63

202540_s_at

3-hydroxy-3-methylglutaryl-Coenzyme A reductase

HMGCR

5q13.3-q14

NM_000859.1

83.8

Above

4.4

old

64

203198_at

cyclin-dependent kinase 9 (CDC2-related kinase)

CDK9

9q34.1

NM_001261.1

83.8

Below

4.8

old

65

203932_at

major histocompatibility complex, class II, DM beta

HLA-DMB

6p21.3

NM_002118.1

83.8

Below

7.9

old

66

204613_at

phospholipase C, gamma 2 (phosphatidylinositol-specific)

PLCG2

16q24.1

NM_002661.1

83.8

Below

3.9

old

67

205267_at

POU domain, class 2, associating factor 1

POU2AF1

11q23.1

NM_006235.1

83.8

Below

11.2

old

68

208650_s_at

CD24 antigen (small cell lung carcinoma cluster 4 antigen)

CD24

6q21

BG327863

83.8

Below

74.7

old

69

208651_x_at

CD24 antigen (small cell lung carcinoma cluster 4 antigen)

CD24

6q21

M58664.1

83.8

Below

52.7

old

70

209995_s_at

T-cell leukemia/lymphoma 1A

TCL1A

14q32.1

BC003574.1

83.8

Below

20166.2

old

71

210038_at

protein kinase C, theta

PRKCQ

10p15

AL137145

83.8

Above

12.7

old

72

211126_s_at

cysteine and glycine-rich protein 2

CSRP2

12q21.1

U46006.1

83.8

Below

18.0

old

73

220068_at

pre-B lymphocyte gene 3

VPREB3

22q11.23

NM_013378.1

83.8

Below

6559.8

new

74

226245_at

cDNA DKFZp451C132

DKFZp451C132

 

U55984

83.8

Above

8.7

new

75

202615_at

cDNA DKFZp686D0521

DKFZp686D0521

 

BF222895

82.2

Above

3.1

old

76

224861_at

cDNA FLJ31057 fis

FLJ31057

 

BF477658

82.2

Above

3.5

new

77

201194_at

selenoprotein W, 1

SEPW1

19q13.3

NM_003009.1

82.0

Above

3.8

old

78

201349_at

solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1

SLC9A3R1

17q25.2

NM_004252.1

82.0

Above

2.9

old

79

202539_s_at

3-hydroxy-3-methylglutaryl-Coenzyme A reductase

HMGCR

5q13.3-q14

AL518627

82.0

Above

3.5

old

80

203588_s_at

transcription factor Dp-2 (E2F dimerization partner 2)

TFDP2

3q23

BG034328

82.0

Above

17.5

old

81

204852_s_at

protein tyrosine phosphatase, non-receptor type 7

PTPN7

1q32.1

NM_002832.1

82.0

Above

9.5

old

82

207434_s_at

FXYD domain containing ion transport regulator 2

FXYD2