Publications

BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
Charles G. Mullighan, Christopher B. Miller, Letha A. Phillips, Ina Radtke, James Dalton, Jing Ma, Deborah White, Timothy P. Hughes, Michelle M. Le Beau, Ching-Hon Pui, Mary V. Relling, Sheila A. Shurtleff and James R. Downing
Nature 2008

Identification of genes associated with chemotherapy cross-resistance and treatment response in childhood acute lymphoblastic leukemia
Sanne Lugthart , Meyling H. Cheok , Monique L. den Boer , Wenjian Yang , Amy Holleman , Cheng Cheng , Ching-Hon Pui , Mary V. Relling , Gritta E. Janka-Schaub , Rob Pieters, William E. Evans

Treatment-specific Changes in Gene Expression Discriminate in vivo Drug
response in Human Leukemia Cells
Meyling H. Cheok, Wenjian Yang, Ching Hon Pui, James R. Downing, CHeng Cheng, Clayton W. Naeve, Mary V. Relling, William E. Evans
Nature Genetics 2003

Pediatric Lymphoblastic Leukemia by Gene Expression Profiling
Eng-Juh Yeoh, Mary E. Ross, Shelia A. Shurtleff, W. Kent Williams, Divyen Patel, Rami Mahfouz, Fred G. Behm, Susana C. Raimondi, Mary V. Relling, Anami Patel, Cheng Cheng, Dario Campana, Dawn Wilkins, Xiaodong Zhou, Jinyan Li, Huiqing Liu, Ching-Hon Pui, William E. Evans, Clayton Naeve, Limsoon Wong, James R. Downing
Cancer Cell 2002 Volume 1:133-143

Gene Expression Profiling of Pediatric Acute Myelogenous Leukemia
Mary E. Ross, Rami Mahfouz, Mihaela Onciu, Hsi-Che Liu, Xiadong Zhou, Guangchun Song, Shelia A. Shurtleff, Stanley Pounds, Cheng Cheng, Jing Ma, Raul C. Riberiro, Jeffrey E. Rubnitz, Kevin Girtman, W. Kent Williams, Susana C. Raimondi, Der-Chemg Liang, Lee-Yung Shih, CHing-Hon Pui & James R. Downing
Blood 2004

Gene-expression patterns in drug resistant acute lymphoblastic leukemia cells and response to treatment.
Amy Holleman, Meyling H. Cheok, Monique L. den Boer, Wenjian Yang, Anjo J.P. Veerman, Karin M. Kazemier, Deqing Pei, Cheng Cheng, Ching-Hon Pui, Mary V. Relling, Gritta E. Janka-Schaub, Rob Pieters, and William E. Evans
2004

Expression of the outcome predictor in acute leukemia 1 (OPAL1) gene is not an independent prognostic factor in patients treated according to COALL or St Jude protocols.
Holleman A, den Boer ML, Cheok MH, Kazemier KM, Pei D, Downing JR, Janka-Schaub GE, Gobel U, Graubner UB, Pui CH, Evans WE, Pieters R.
Blood. 2006 Sep 15;108(6): 1984-90.

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
Charles G. Mullighan, Salil Goorha, Ina Radtke, Christopher B. Miller, Elaine Coustan-Smith, James D. Dalton, Kevin Girtman, Susan Mathew, Jing Ma, Stanley B. Pounds, Xiaoping Su, Ching-Hon Pui, Mary V. Relling, William E. Evans, Sheila A. Shurtleff and James R. Downing