AC  M00221
XX
ID  V$SREBP1_02
XX
DT  16.10.1995 (created); ewi.
DT  16.10.1995 (updated); ewi.
XX
NA  SREBP-1
XX
DE  sterol regulatory element-binding protein 1
XX
BF  T01556; SREBP-1a; Species: human, Homo sapiens.
BF  T01562; ADD1; Species: rat, Rattus norvegicus.
BF  T01559; SREBP-1; Species: hamster, Cricetulus griseus.
BF  T01558; SREBP-1c; Species: human, Homo sapiens.
BF  T01557; SREBP-1b; Species: human, Homo sapiens.
XX
P0      A      C      G      T
01      0      1      3      3      K
02      5      0      2      0      A
03      0      0      0      7      T
04      0      7      0      0      C
05      7      0      0      0      A
06      0      7      0      0      C
07      0      7      0      0      C
08      0      7      0      0      C
09      0      7      0      0      C
10      7      0      0      0      A
11      0      7      0      0      C
XX
BA  7 selected binding sequences
XX
BS  R07517; Start: 14; Length: 11; Gaps: -; Orientation: p.
BS  R07518; Start: 14; Length: 11; Gaps: -; Orientation: p.
BS  R07519; Start: 14; Length: 11; Gaps: -; Orientation: p.
BS  R07520; Start: 5; Length: 11; Gaps: -; Orientation: p.
BS  R07521; Start: 11; Length: 11; Gaps: -; Orientation: p.
BS  R07522; Start: 14; Length: 11; Gaps: -; Orientation: p.
BS  R07523; Start: 14; Length: 11; Gaps: -; Orientation: p.
XX
CC  5 rounds of selection of random 16-mers bound to bacterially 
CC  expressed protein; sequences that lead to a non-E-box consensus
XX
RN  [1]
RX  MEDLINE; 95257939.
RA  Kim J. B., Spotts G. D., Halvorsen Y.-D., Shih H.-M., 
RA  Ellenberger T., Towle H. C., Spiegelman B. M.
RT  Dual DNA binding specificity of ADD1/SREBP1 controlled 
RT  by a single amino acid in the basic helix-loop-helix domain
RL  Mol. Cell. Biol. 15:2582-2588 (1995).
XX
//